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Chemical Structure : SR 8278
CAS No.: 1254944-66-5
Catalog No.: PC-62691Not For Human Use, Lab Use Only.
SR 8278 is the first synthetic antagonist of the nuclear heme receptor Rev-ErbA, inhibits the REV-ERBα transcriptional repression activity with EC50 of 0.47 uM in HEK293 cells..
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $188 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | $548 | In stock | |
| 100 mg | Get quote |
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SR 8278 is the first synthetic antagonist of the nuclear heme receptor Rev-ErbA, inhibits the REV-ERBα transcriptional repression activity with EC50 of 0.47 uM in HEK293 cells.
| M.Wt | 361.48 | |
| Formula | C18H19NO3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1,2,3,4-Tetrahydro-2-[[5-(methylthio)-2-thienyl]carbonyl]-3-isoquinolinecarboxylic acid ethyl ester |
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1. Kojetin D, et al. ACS Chem Biol. 2011 Feb 18;6(2):131-4.
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