| Cat. No. |
Product Name |
Information |
| PC-22073 |
SR12418
REV-ERB agonist
|
SR12418 (SR-12418) is a potent, selective REV-ERB ligand/agonist with IC50 of 68 nM and 119 nM for REV-ERBα and REV-ERBβ, respectively, in TR-FRET biochemical assay. |
| PC-20752 |
STL1267
REV-ERB agonist
|
STL1267 is a specific, high affinity synthetic agonist of nuclear receptor REV-ERB with EC50 of 0.13 uM and Ki of 0.16 uM, binds directly to the ligand binding domain (LBD) of REV-ERB. |
| PC-47043 |
SR9009
REV-ERB agonist
|
Stenabolic (SR9009) is a potent, synthetic REV-ERB agonist with IC50s of 670 nM and 800 nM for REV-ERB-α and for REV-ERB-β, respectively. |
| PC-62691 |
SR 8278
Rev-ErbA inhibitor
|
SR 8278 is the first synthetic antagonist of the nuclear heme receptor Rev-ErbA, inhibits the REV-ERBα transcriptional repression activity with EC50 of 0.47 uM in HEK293 cells.. |
| PC-62690 |
GSK2945
REV-ERB agonist
|
GSK2945 is a potent and selective small molecule Rev-Erbα agonist with EC50 of 50 nM, displays >1,000-fold selectivity over LXRα. |
| PC-61357 |
ARN-5187
REV-ERB inhibitor
|
ARN-5187 (ARN5187) is a lysosomotropic REV-ERB ligand that has a dual inhibitory activity toward REV-ERB-mediated transcriptional regulation and autophagy. |
| PC-45117 |
SR9011 hydrochloride
REV-ERB agonist
|
SR9011 hydrochloride is a potent, small molecule nuclear receptors REV-ERBα/β agonist with IC50 of 670/800 nM, respectively. |
| PC-45116 |
SR9011
REV-ERB agonist
|
SR9011 is a potent, small molecule nuclear receptors REV-ERBα/β agonist with IC50 of 670/800 nM, respectively. |
| PC-43929 |
GSK4112
REV-ERB agonist
|
GSK4112 (SR6452) is a potent and selective small molecule Rev-erbα agonist with EC50 of 0.4 uM in biochemical assays. |
