Cat. No. |
Product Name |
Information |
PC-47043 |
SR9009
REV-ERB agonist
|
Stenabolic (SR9009) is a potent, synthetic REV-ERB agonist with IC50s of 670 nM and 800 nM for REV-ERB-α and for REV-ERB-β, respectively. |
PC-62691 |
SR 8278
Rev-ErbA inhibitor
|
SR 8278 is the first synthetic antagonist of the nuclear heme receptor Rev-ErbA, inhibits the REV-ERBα transcriptional repression activity with EC50 of 0.47 uM in HEK293 cells.. |
PC-20752 |
STL1267
REV-ERB agonist
|
STL1267 is a specific, high affinity synthetic agonist of nuclear receptor REV-ERB with EC50 of 0.13 uM and Ki of 0.16 uM, binds directly to the ligand binding domain (LBD) of REV-ERB. |
PC-62690 |
GSK-2945
|
GSK-2945 is a potent and selective small molecule Rev-Erbα agonist with EC50 of 50 nM, displays >1,000-fold selectivity over LXRα. |