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Chemical Structure : SR9009
CAS No.: 1379686-30-2
Catalog No.: PC-47043Not For Human Use, Lab Use Only.
Stenabolic (SR9009) is a potent, synthetic REV-ERB agonist with IC50s of 670 nM and 800 nM for REV-ERB-α and for REV-ERB-β, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $218 | In stock | |
| 100 mg | Get quote |
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Stenabolic (SR9009) is a potent, synthetic REV-ERB agonist with IC50s of 670 nM and 800 nM for REV-ERB-α and for REV-ERB-β, respectively.
SR9009 decreases circadian locomotor activity during the dark phase and to alter the expression pattern of core clock genes in the hypothalami of mice.
SR9009 (i.p. two times a day for 30 days) displays decreased fat mass and markedly improved dyslipidemia and hyperglycemia.
| M.Wt | 437.9 | |
| Formula | C20H24ClN3O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3-[[[(4-chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-1-pyrrolidinecarboxylic acid ethyl ester |
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1. Laura A Solt, et al. Nature. 2012 Mar 29;485(7396):62-8.
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