SRI-29132

Chemical Structure : SRI-29132

Catalog No.: PC-24618Not For Human Use, Lab Use Only.

SRI-29132 is a potent, highly selective and brain-permeable LRRK2 inhibitor with IC50 of 146 nM and 75 nM in WT LRRK2 and G2019S-LRRK2 cis-autophosphorylation kinase assays respectively.

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

SRI-29132 is a potent, highly selective and brain-permeable LRRK2 inhibitor with IC50 of 146 nM and 75 nM in WT LRRK2 and G2019S-LRRK2 cis-autophosphorylation kinase assays respectively.

Physicochemical Properties

M.Wt	387.52
Formula	C18H21N5OS2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(piperidin-1-yl)-2-((3-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)butan-1-one

References

1. Liu Z, et al. J Biol Chem. 2014 Nov 21;289(47):32937-51.

2. Moukha-Chafiq O, et al. J Med Chem. 2025 May 12. doi: 10.1021/acs.jmedchem.4c02473.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

SRI-29132

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.