Chemical Structure : SRT2104
CAS No.: 1093403-33-8
Catalog No.: PC-47061Not For Human Use, Lab Use Only.
SRT2104 (GSK2245840) is a highly selective small molecule activator of the NAD+ dependent deacetylase SIRT1.
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SRT2104 (GSK2245840) is a highly selective small molecule activator of the NAD+ dependent deacetylase SIRT1, increases Sirt1 protein with no effect on Sirt1 mRNA level.
M.Wt | 516.638 | |
Formula | C26H24N6O2S2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-methyl-N-[2-[3-(4-morpholinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-(3-pyridinyl)-5-thiazolecarboxamide |
1. Ethan Hoffmann, et al. Br J Clin Pharmacol. 2013 Jan;75(1):186-96.
2. Mercken EM, et al. Aging Cell. 2014 Oct;13(5):787-96.
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