SRT3109 (AZD-5122) | CXCR2 antagonist | Probechem Biochemicals

Chemical Structure : SRT3109

CAS No.: 1204707-71-0

SRT3109 (SRT-3109, AZD-5122, AZD5122)

Catalog No.: PC-28151Not For Human Use, Lab Use Only.

SRT3109 (AZD-5122) is a potent, selective antagonist of CXCR2 with pIC50 of 8.2, significantly reduces pancreatic tissue edema and inflammation infiltration scores.

Packing	Price	Stock
10 mg	$88	In stock
25 mg	$148	In stock
50 mg	$248	In stock
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Biological Activity

SRT3109 (AZD-5122) is a potent, selective antagonist of CXCR2 with pIC50 of 8.2, significantly reduces pancreatic tissue edema and inflammation infiltration scores.
SRT3109 significantly reduced the mRNA of inflammatory factors IL-1β, TNF-α, and IL-6 in AP pancreatic tissue.

Physicochemical Properties

M.Wt	475.53
Formula	C18H23F2N5O4S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-(2,3-difluorobenzylthio)-6-((2R,3R)-3,4-dihydroxybutan-2-ylamino)pyrimidin-4-yl)azetidine-1-sulfonamide

References

1. Patent WO2010007427 A1 2010-01-21.

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SRT3109 (SRT-3109, AZD-5122, AZD5122)

Biological Activity

Physicochemical Properties

References

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