Chemical Structure : SRX3207
CAS No.: 2254693-15-5
Catalog No.: PC-38196Not For Human Use, Lab Use Only.
SRX3207 (SRX-3207) is a potent, orally active dual Syk/PI3K inhibitor with IC50 of 39.9/244/388 nM for Syk/PI3Kα/PI3Kδ, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $248 | In stock | |
| 10 mg | $388 | In stock | |
| 25 mg | $598 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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SRX3207 (SRX-3207) is a potent, orally active dual Syk/PI3K inhibitor with IC50 of 39.9/244/388 nM for Syk/PI3Kα/PI3Kδ, respectively.
SRX3207 potently blocks immunosuppressive gene expression effectively at very low dose compared to commercially available p110γ inhibitor (IPI-549) or Syk inhibitor (R488) alone, didn't affect T cell proliferation.
| M.Wt | 555.657 | |
| Formula | C29H29N7O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3-[4-[[4-[4-(1-Azetidinylmethyl)-3-methyl-1H-pyrazol-1-yl]-2-pyrimidinyl]amino]phenyl]-5-(4-morpholinyl)-7H-thieno[3,2-b]pyran-7-one |
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1. Shweta Joshi, et al. Mol Cancer Ther. 2020 Mar;19(3):755-764.

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