Catalog No.: PC-35008Not For Human Use, Lab Use Only.
ST-148 is a potent, broad-spetrum inhibitor of dengue virus (DENV) replication, inhibits DENV-2 wth EC50 of 16 nM in viral titer reduction assays, interacts with the DENV capsid protein.
ST-148 is a potent, broad-spetrum inhibitor of dengue virus (DENV) replication, inhibits DENV-2 wth EC50 of 16 nM in viral titer reduction assays, interacts with the DENV capsid protein.
ST-148 exhibits a broad range of potencies with EC50 of 0.512, 1.150, and 2.832 uM for DENV-3, -4, and -1, respectively.
ST-148 significantly reduced viremia and viral load in vital organs and tended to lower cytokine levels in the plasma in a nonlethal model of DENV infection in AG129 mice.
