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ST 016907

Chemical Structure : ST 016907

CAS No.: 329071-59-2

ST 016907 (ST016907)

Catalog No.: PC-61467Not For Human Use, Lab Use Only.

ST 016907 is a potent CCR4 antagonist that blocked CCL22- and CCL17-mediated migration of human peripheral blood CD4+CD25+ Treg and Th2 cells ex-vivo and murine Tregs in-vivo.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    ST 016907 is a potent CCR4 antagonist that blocked CCL22- and CCL17-mediated migration of human peripheral blood CD4+CD25+ Treg and Th2 cells ex-vivo and murine Tregs in-vivo.

    Physicochemical Properties

    M.Wt 636.555
    Formula C24H15Cl2N5O4S4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(2,6-dichlorophenyl)-2-((6-(2-((6-nitrobenzo[d]thiazol-2-yl)thio)acetamido)benzo[d]thiazol-2-yl)thio)acetamide

    References

    1. Bayry J, et al. Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10221-6.

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