Chemical Structure : ST1535
CAS No.: 496955-42-1
Catalog No.: PC-70072Not For Human Use, Lab Use Only.
ST1535 is a potent, selective A2A adenosine receptor antagonist with Ki of 6.6 nM.
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ST1535 is a potent, selective A2A adenosine receptor antagonist with Ki of 6.6 nM.
ST1535 displays 10, 58 and >160-fold selectivity over A1, A2B and A3 receptors, respectively.
ST1535 increases locomotor activity in animal models of Parkinson׳s disease.
M.Wt | 272.316 | |
Formula | C12H16N8 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-butyl-9-methyl-8-(2H-1,2,3-triazol-2-yl)-9H-purin-6-amine |
1. Minetti P, et al. J Med Chem. 2005 Nov 3;48(22):6887-96.
2. Rose S, et al. Eur J Pharmacol. 2006 Sep 28;546(1-3):82-7.
3. Rose S, et al. Brain Res. 2007 Feb 16;1133(1):110-4.
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