ST1535 |CAS:496955-42-1 Probechem Biochemicals

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Chemical Structure : ST1535

CAS No.: 496955-42-1

ST1535 (ST 1535;ST-1535)

Catalog No.: PC-70072Not For Human Use, Lab Use Only.

ST1535 is a potent, selective A2A adenosine receptor antagonist with Ki of 6.6 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ST1535 is a potent, selective A2A adenosine receptor antagonist with Ki of 6.6 nM.
ST1535 displays 10, 58 and >160-fold selectivity over A1, A2B and A3 receptors, respectively.
ST1535 increases locomotor activity in animal models of Parkinson׳s disease.

Physicochemical Properties

M.Wt	272.316
Formula	C12H16N8
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-butyl-9-methyl-8-(2H-1,2,3-triazol-2-yl)-9H-purin-6-amine

References

1. Minetti P, et al. J Med Chem. 2005 Nov 3;48(22):6887-96.

2. Rose S, et al. Eur J Pharmacol. 2006 Sep 28;546(1-3):82-7.

3. Rose S, et al. Brain Res. 2007 Feb 16;1133(1):110-4.

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ST1535 (ST 1535;ST-1535)

Biological Activity

Physicochemical Properties

References

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