STF-083010 (STF083010)

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Chemical Structure : STF-083010

CAS No.: 307543-71-1

Catalog No.: PC-44755Not For Human Use, Lab Use Only.

STF-083010 (STF083010) is a potent and selective IRE1 endoribonuclease inhibitor without affecting IRE1 kinase activity.

Packing	Price	Stock
10 mg	$58	In stock
25 mg	$88	In stock
50 mg	$128	In stock
100 mg	$198	In stock
250 mg		Get quote

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

STF-083010 (STF083010) is a potent and selective IRE1 endoribonuclease inhibitor without affecting IRE1 kinase activity.
STF-083010 shows significant antimyeloma activity in model human MM xenografts.

Physicochemical Properties

M.Wt	317.3828
Formula	C15H11NO3S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Thiophenesulfonamide, N-[(2-hydroxy-1-naphthalenyl)methylene]-

References

1. Papandreou I, et al. Blood. 2011 Jan 27;117(4):1311-4.

2. Chien W, et al. Oncotarget. 2014 Jul 15;5(13):4881-94.

3. Sun H, et al. Oncotarget. 2016 Apr 5;7(14):18736-49.

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