STIMA 1 |CAS:91634-12-7 Probechem Biochemicals

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Chemical Structure : STIMA 1

CAS No.: 91634-12-7

STIMA 1 (STIMA1)

Catalog No.: PC-62083Not For Human Use, Lab Use Only.

STIMA 1 is a small molecule mutant p53 reactivator that can stimulate mutant p53 DNA binding in vitro, induces expression of p53 target proteins and triggers apoptosis in mutant p53-expressing human tumor cells..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

STIMA 1 is a small molecule mutant p53 reactivator that can stimulate mutant p53 DNA binding in vitro, induces expression of p53 target proteins and triggers apoptosis in mutant p53-expressing human tumor cells.

Physicochemical Properties

M.Wt	172.187
Formula	C10H8N2O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-ethenyl-1H-quinazolin-4-one

References

1. Zache N, et al. Mol Oncol. 2008 Jun;2(1):70-80.

2. Bykov VJ, et al. FEBS Lett. 2014 Aug 19;588(16):2622-7.

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STIMA 1 (STIMA1)

Biological Activity

Physicochemical Properties

References

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