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STK189682

Chemical Structure : STK189682

CAS No.: 765922-18-7

STK189682

Catalog No.: PC-26292Not For Human Use, Lab Use Only.

STK189682 is a potent small molecule inhibitor of RNA helicases MDA5, LGP2, and DDX1 with IC50 of 7 uM, 7 uM and 5 uM in ATPase assays.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

STK189682 is a potent small molecule inhibitor of RNA helicases MDA5, LGP2, and DDX1 with IC50 of 7 uM, 7 uM and 5 uM in ATPase assays.

Physicochemical Properties

M.Wt 452.50
Formula C21H16N4O4S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-((2'-benzamido-4'-methyl-[4,5'-bithiazol]-2-yl)amino)-2-hydroxybenzoic acid

References

1. Wang X, et al. Eur J Med Chem. 2026 Feb 26;309:118724.

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