Chemical Structure : SU1261
CAS No.: 3061890-98-7
Catalog No.: PC-22934Not For Human Use, Lab Use Only.
SU1261 is a potent, selective inhibitor of IKKα with Ki of 10 nM, >60-fold selective over IKKβ.
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SU1261 is a potent, selective inhibitor of IKKα with Ki of 10 nM, >60-fold selective over IKKβ, selectively perturbs non-canonical NF-κB signalling whilst avoiding any significant impact upon the IKKβ-mediated canonical NF-κB pathway in cells.
| M.Wt | 431.50 | |
| Formula | C27H21N5O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
5-(2-(3-(benzyloxy)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-indazol-3-amine |
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1. Christopher Riley, et al. Molecules. 2024 Jul 26;29(15):3515.

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