Chemical Structure : SU14813 maleate
CAS No.:
849643-15-8
SU14813 maleate
(SU-14813 maleate)
Catalog No. : PC-42623Not For Human Use, Lab Use Only.
SU14813 maleate is a broad-spectrum RTKs inhibitor with IC50 ranging from 2 to 50 nM for VEGFR-1, VEGFR-2, PDGFRs, KIT, FLT3, and CSF1R/FMS.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4262301
Biological Activity
SU14813 maleate is a broad-spectrum RTKs inhibitor with IC50 ranging from 2 to 50 nM for VEGFR-1, VEGFR-2, PDGFRs, KIT, FLT3, and CSF1R/FMS.
Physicochemical Properties
M.Wt
558.5554
Formula
C27H31FN4O8
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
1H-Pyrrole-3-carboxamide, 5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-(4-morpholinyl)propyl]-2,4-dimethyl-, (2Z)-2-butenedioate (1:1)
References
1. Patyna S, et al. Mol Cancer Ther. 2006 Jul;5(7):1774-82.
2. Hu-Lowe D, et al. Mol Cancer Ther. 2011 Nov;10(11):2015.
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