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Chemical Structure : SUCNR1 inhibitor 20
Catalog No.: PC-72380Not For Human Use, Lab Use Only.
SUCNR1 inhibitor 20 is a potent, selective inhibitor (antagonist) of GPCR SUCNR1 (succinate receptor 1/GPR91) with IC50 of 88 nM.
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SUCNR1 inhibitor 20 is a potent, selective inhibitor (antagonist) of GPCR SUCNR1 (succinate receptor 1/GPR91) with IC50 of 88 nM.
SUCNR1 (GPR91) senses the citric cycle intermediate succinate and is implicated in various pathological conditions such as rheumatoid arthritis, liver fibrosis, or obesity.
| M.Wt | 518.917 | |
| Formula | C26H22ClF3N2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Juraj Velcicky, et al. J Med Chem. 2020 Sep 10;63(17):9856-9875.
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