Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

You are here:Home-Chemical Inhibitors & Agonists-Others-Other Targets-SUCNR1 inhibitor 20
SUCNR1 inhibitor 20

Chemical Structure : SUCNR1 inhibitor 20

CAS No.: 2711753-52-3

SUCNR1 inhibitor 20 (GPR91 antagonist)

Catalog No.: PC-72380Not For Human Use, Lab Use Only.

SUCNR1 inhibitor 20 is a potent, selective inhibitor (antagonist) of GPCR SUCNR1 (succinate receptor 1/GPR91) with IC50 of 88 nM.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    SUCNR1 inhibitor 20 is a potent, selective inhibitor (antagonist) of GPCR SUCNR1 (succinate receptor 1/GPR91) with IC50 of 88 nM.
    SUCNR1 (GPR91) senses the citric cycle intermediate succinate and is implicated in various pathological conditions such as rheumatoid arthritis, liver fibrosis, or obesity.

    Physicochemical Properties

    M.Wt 518.917
    Formula C26H22ClF3N2O4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (R)-2-(2-(4'-chloro-2,2'-difluoro-5'-(piperidin-3-yloxy)-[1,1'-biphenyl]-3-carboxamido)-5-fluorophenyl)acetic acid

    References

    1. Juraj Velcicky, et al. J Med Chem. 2020 Sep 10;63(17):9856-9875.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: