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SW394703

Chemical Structure : SW394703

CAS No.: 1357638-86-8

SW394703 (SW 394703)

Catalog No.: PC-21051Not For Human Use, Lab Use Only.

SW394703 is a novel DDB1-dependent molecular glue degrader for cyclin K, SW394703 is toxic to HCT116 cells (IC50=1.2 uM).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SW394703 is a novel DDB1-dependent molecular glue degrader for cyclin K, SW394703 is toxic to HCT116 cells (IC50=1.2 uM).

Physicochemical Properties

M.Wt 336.40
Formula C19H20N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

O=C(N[C@H](C)C(NC1=NC2=CC=CC=C2N1)=O)C3=CC(C)=CC(C)=C3

References

1. Thu P. Nguyen, et al. Cell Chemical Biology 2023.

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