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Chemical Structure : SX-682
CAS No.: 1648843-04-2
Catalog No.: PC-73125Not For Human Use, Lab Use Only.
SX-682 (SX682) is a potent, allosteric, orally bioavailable inhibitor of CXCR1 and CXCR2.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $218 | In stock | |
| 25 mg | $418 | In stock | |
| 50 mg | $728 | In stock | |
| 100 mg | $1080 | In stock | |
| 1 g | Get quote |
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SX-682 (SX682) is a potent, allosteric, orally bioavailable inhibitor of CXCR1 and CXCR2.
SX-682 enhances tumor infiltration, activation, and the therapeutic efficacy of adoptively transferred NK cells.
SX-682 significantly inhibits trafficking of PMN-MDSCs without altering CXCR2 ligand expression.
SX-682 enhances T cell-based immunotherapeutic efficacy.
| M.Wt | 467.202 | |
| Formula | C19H14BF4N3O4S | |
| Appearance | Solid | |
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1. Lu X, et al. Nature. 2017 Mar 30;543(7647):728-732.
2. Sun L, et al. JCI Insight. 2019 Apr 4;4(7). pii: 126853. doi: 10.1172/jci.insight.126853.
3. Greene S, et al. Clin Cancer Res. 2020 Mar 15;26(6):1420-1431.
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