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Chemical Structure : SYC-1307
Catalog No.: PC-23170Not For Human Use, Lab Use Only.
SYC-1307 is a potent, allosteric inhibitor of flavivirus NS2B-NS3 protease with IC50 of 0.2, 0.59, 0.59 and 0.78 uM for ZIKV, DENV2, DENV3 and WNV NS2B-NS3 respectively, shows submicromolar anti-orthoflaviviral efficacy in cells (EC50=0.3-0.6 uM).
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SYC-1307 is a potent, allosteric inhibitor of flavivirus NS2B-NS3 protease with IC50 of 0.2, 0.59, 0.59 and 0.78 uM for ZIKV, DENV2, DENV3 and WNV NS2B-NS3 respectively, shows submicromolar anti-orthoflaviviral efficacy in cells (EC50=0.3-0.6 uM).
| M.Wt | 440.55 | |
| Formula | C27H28N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Nie S, et al. J. Med. Chem. 2021;64:2777–2800.
2. Lorenzo Cavina, et al. Molecules. 2024 Aug 27;29(17):4047.
3. Yao Y, et al. J. Am. Chem. Soc. 2019;141:6832–6836.
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