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Chemical Structure : SZU-106
Catalog No.: PC-49146Not For Human Use, Lab Use Only.
SZU-106 is a small molecule TLR7 agonist, selectively activates TLR7 and increases the expression of SEAP by activating the NF-κB pathway.
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SZU-106 is a small molecule TLR7 agonist, selectively activates TLR7 and increases the expression of SEAP by activating the NF-κB pathway.
SZU-106 (0.5-10 μM) increased the release of interferon (IFN)-γ and IL-6 in a dose-dependent manner after 24 h of treatment in mouse splenic lymphocytes.
SZU-106 with a pegylated linker could produce a novel whole-tumor-cell vaccine, which induced immune-activating responses in both in vitro and in vivo experiments.
| M.Wt | 603.633 | |
| Formula | C27H37N7O9 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Huju Chi, et al. Cells. 2022 Jun 21;11(13):1986.
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