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Chemical Structure : Saframycin A
Catalog No.: PC-70241Not For Human Use, Lab Use Only.
Saframycin A is a heterocyclic quinone antibiotic that inhibits RNA synthesis in vivo and in vitro.
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Saframycin A is a heterocyclic quinone antibiotic that inhibits RNA synthesis in vivo and in vitro.
Saframycin A shows potent antiproliferative effects in leukemia- and tumor-derived cells.
Saframycin A induces nuclear translocation of GAPDH in cancer cells.
| M.Wt | 562.579 | |
| Formula | C29H30N4O8 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Xing C, et al. Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):5862-6.
2. Ishiguro K, et al. Biochemistry. 1978 Jun 27;17(13):2545-50.
3. Spencer JR, et al. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4884-8.
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