Chemical Structure : Saikosaponin D
CAS No.: 20874-52-6
Catalog No.: PC-27755Not For Human Use, Lab Use Only.
Saikosaponin D is an active component isolated from Bupleurum falcatum, inhibits activated T lymphocyte proliferation by downregulating the NF-κB, NF-AT, and AP-1 signaling pathways, suppresses enterovirus A71 infection (EV-A71) by inhibiting autophagy, also potently inhibits the proliferation and invasion of cancer cells, induces the apoptosis of cancer cells, and suppresses angiogenesis.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $78 | In stock | |
| 25 mg | $128 | In stock | |
| 50 mg | $198 | In stock | |
| 100 mg | Get quote |
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Saikosaponin D is an active component isolated from Bupleurum falcatum, inhibits activated T lymphocyte proliferation by downregulating the NF-κB, NF-AT, and AP-1 signaling pathways, suppresses enterovirus A71 infection (EV-A71) by inhibiting autophagy, also potently inhibits the proliferation and invasion of cancer cells, induces the apoptosis of cancer cells, and suppresses angiogenesis.
| M.Wt | 780.98 | |
| Formula | C42H68O13 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-3,5-Dihydroxy-2-(((3S,4R,4aR,6aR,6bS,8R,8aS,12aR,12bS,14aR,14bS)-8-hydroxy-4-(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,9,10,11,12,12a,14a,14b-octadecahydro-12b,8a-(epoxymethano)picen-3-yl)oxy)-6-methyltetrahydro-2H-pyran-4-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol |
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1. Li C, et al. Signal Transduct Target Ther. 2019 Feb 22;4:4.
2. Wong VK, et al. J. Cell. Biochem. 2009;107:303–315.
3. Wong VK, et al. Evid.-Based Complement. Altern. Med. 2013;2013:745295.

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