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Saroglitazar

Chemical Structure : Saroglitazar

CAS No.: 495399-09-2

Saroglitazar (PPARα agonist)

Catalog No.: PC-45752Not For Human Use, Lab Use Only.

Saroglitazar is a PPAR agonist with predominant PPARα and moderate PPARγ activity with EC50 of 0.65 pM and 3 nM respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Saroglitazar is a PPAR agonist with predominant PPARα and moderate PPARγ activity with EC50 of 0.65 pM and 3 nM respectively.
Saroglitazar has been developed for the treatment of dyslipidaemia and has favourable effects on glycaemic parameters in type 2 diabetes mellitus.

Physicochemical Properties

M.Wt 439.567
Formula C25H29NO4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: 10 mM

Chemical Name/SMILES

Benzenepropanoic acid, α-ethoxy-4-[2-[2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrol-1-yl]ethoxy]-, (αS)-

References

1. Agrawal R. Curr Drug Targets. 2014 Feb;15(2):151-5.

2. Jani RH, et al. Clin Drug Investig. 2013 Nov;33(11):809-16.

3. Jain MR, et al. Pharmacol Res Perspect. 2015 Jun;3(3):e00136.

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