Chemical Structure : Saroglitazar magnesium salt
CAS No.: 1639792-20-3
Catalog No.: PC-45753Not For Human Use, Lab Use Only.
A novel PPAR agonist with predominant PPARα and moderate PPARγ activity with EC50 of 0.65 pM and 3 nM respectively.
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A novel PPAR agonist with predominant PPARα and moderate PPARγ activity with EC50 of 0.65 pM and 3 nM respectively; has been developed for the treatment of dyslipidaemia and has favourable effects on glycaemic parameters in type 2 diabetes mellitus.
Diabetes
Approved
M.Wt | 450.71 | |
Formula | C25H28NO4S.1/2Mg | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Benzenepropanoic acid, α-ethoxy-4-[2-[2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrol-1-yl]ethoxy]-,magnesium salt (2:1),(αS)-, |
1. Agrawal R. Curr Drug Targets. 2014 Feb;15(2):151-5.
2. Jani RH, et al. Clin Drug Investig. 2013 Nov;33(11):809-16.
3. Jain MR, et al. Pharmacol Res Perspect. 2015 Jun;3(3):e00136.
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