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Chemical Structure : Saxagliptin hydrate
CAS No.: 945667-22-1
Catalog No.: PC-42510Not For Human Use, Lab Use Only.
Saxagliptin (BMS-477118) hydrate is a highly potent, long-acting, orally active DPP4 inhibitor with Ki of 0.6 nM.
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|---|---|---|---|
| 25 mg | $78 | In stock | |
| 50 mg | $118 | In stock | |
| 100 mg | $198 | In stock | |
| 250 mg | Get quote |
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Saxagliptin (BMS-477118) hydrate is a highly potent, long-acting, orally active DPP4 inhibitor with Ki of 0.6 nM.
Saxagliptin shows no CYP3A4 inhibition up to 100 uM, and good oral exposure.
| M.Wt | 333.4253 | |
| Formula | C18H27N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, hydrate (1:1), (1S,3S,5S)- |
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1. Augeri DJ, et al. J Med Chem. 2005 Jul 28;48(15):5025-37.
2. Kim YB, et al. Arch Biochem Biophys. 2006 Jan 1;445(1):9-18.
3. Ikeda J, et al. J Pharmacol Sci. 2016 Sep;132(1):65-70.
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