Seco Rapamycin |CAS:147438-27-5 Probechem Biochemicals

Chemical Structure : Seco Rapamycin

Catalog No.: PC-35070Not For Human Use, Lab Use Only.

Seco-rapamycin is the first in vivo open-ring metabolite of rapamycin that does not affect mTOR..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Seco-rapamycin is the first in vivo open-ring metabolite of rapamycin that does not affect mTOR.

M.Wt	914.17
Formula	C51H79NO13
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Piperidinecarboxylic acid, 1-[oxo[tetrahydro-2-hydroxy-6-[14-hydroxy-22-(4-hydroxy-3-methoxycyclohexyl)-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15,19-docosapentaenyl]-3-methyl-2H-pyran-2-yl]acetyl]-, [2R-[2α,2(S*),3α

1. Osmulski PA, et al. Mol Pharmacol. 2013 Jul;84(1):104-13.

2. Cai P, et al. Drug Metab Dispos. 2007 Sep;35(9):1554-63.