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Seco Rapamycin sodium salt

Chemical Structure : Seco Rapamycin sodium salt

CAS No.: 148554-65-8

Seco Rapamycin sodium salt (Secorapamycin A monosodium)

Catalog No.: PC-45649Not For Human Use, Lab Use Only.

Seco-rapamycin is the first in vivo open-ring metabolite of rapamycin that does not affect mTOR..

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Purity & Documentation Purity: 97.39% Select Batch:

Biological Activity

Seco-rapamycin is the first in vivo open-ring metabolite of rapamycin that does not affect mTOR.

Physicochemical Properties

M.Wt 936.1537
Formula C51H78NNaO13
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
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Solubility

DMSO: ≥ 46 mg/mL

Chemical Name/SMILES

2-Piperidinecarboxylic acid, 1-[oxo[tetrahydro-2-hydroxy-6-[14-hydroxy-22-(4-hydroxy-3-methoxycyclohexyl)-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15,19-docosapentaenyl]-3-methyl-2H-pyran-2-yl]acetyl]-, monosodium salt, [2R-[2α,2(S*),3α

References

1. Osmulski PA, et al. Mol Pharmacol. 2013 Jul;84(1):104-13.

2. Cai P, et al. Drug Metab Dispos. 2007 Sep;35(9):1554-63.

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