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Chemical Structure : Selgantolimod
CAS No.: 2004677-13-6
Catalog No.: PC-36098Not For Human Use, Lab Use Only.
Selgantolimod (GS-9688; GS9688) is a potent, selective and orally bioavailable TLR8 agonist with IL-12p40 EC50 of 220 nM, >100-fold TLR7 selectivity (IFN-α, EC50 >50 uM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $358 | In stock | |
| 10 mg | $558 | In stock | |
| 25 mg | Get quote | ||
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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| M.Wt | 293.346 | |
| Formula | C14H20FN5O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(2R)-2-[(2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-yl)amino]-2-methylhexan-1-ol |
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1. U.S. Pat. Appl. Publ. (2017), US 20170071944 A1 20170316.
2. PCT Int. Appl. (2016), WO 2016141092 A1 20160909.
3. Daffis S, et al. Hepatology. 2021 Jan;73(1):53-67.
4. Mackman RL, et al. J Med Chem. 2020 Sep 24;63(18):10188-10203.
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