Catalog No.: PC-70326Not For Human Use, Lab Use Only.
Seriniquinone (S 747855) is a melanoma-selective anticancer agent (IC50=30 nM, Malme-3M cell line), induces cell death by autophagocytosis, targeting the cancer-protective protein dermcidin.
Seriniquinone (S 747855) is a melanoma-selective anticancer agent (IC50=30 nM, Malme-3M cell line), induces cell death by autophagocytosis, targeting the cancer-protective protein dermcidin.
Seriniquinone demonstrates potent activity over a select set of tumor cell lines with particular selectivity toward melanoma cell lines.
Seriniquinone increases the cleavage of caspases 3, 7, and 9 and PARP in HCT-116 cells.
Seriniquinone causes an increasing level of DCD expression directly correlated with cell line selectivity,
