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SirReal1.1

Chemical Structure : SirReal1.1

CAS No.: 1862238-00-3

SirReal1.1 (SirReal 1.1)

Catalog No.: PC-21305Not For Human Use, Lab Use Only.

SirReal1.1 is a potent, selective inhibitor of Sirtuin 2 (Sirt2) with IC50 of 0.16 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SirReal1.1 is a potent, selective inhibitor of Sirtuin 2 (Sirt2) with IC50 of 0.16 uM.

Physicochemical Properties

M.Wt 557.69
Formula C28H27N7O2S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(5-(3-((1-benzyl-1H-1,2,3-triazol-4-yl)methoxy)benzyl)thiazol-2-yl)-2-((4,6-dimethylpyrimidin-2-yl)thio)acetamide

References

1. Matthias Schiedel, et al. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6.

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