SirReal1.2 | Sirtuin 2 inhibitor | Probechem Biochemicals

Chemical Structure : SirReal1.2

Catalog No.: PC-21306Not For Human Use, Lab Use Only.

SirReal1.2 is a potent, selective inhibitor of Sirtuin 2 (Sirt2) with IC50 of 0.12 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SirReal1.2 is a potent, selective inhibitor of Sirtuin 2 (Sirt2) with IC50 of 0.12 uM.

M.Wt	525.65
Formula	C24H27N7O3S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((4,6-dimethylpyrimidin-2-yl)thio)-N-(5-(3-((1-(2-methoxyethyl)-1H-1,2,3-triazol-4-yl)methoxy)benzyl)thiazol-2-yl)acetamide

1. Matthias Schiedel, et al. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6.