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Sodium danshensu

Chemical Structure : Sodium danshensu

CAS No.: 81075-52-7

Sodium danshensu (Danshensu sodium, Salvianic acid A sodium, SDSS)

Catalog No.: PC-28258Not For Human Use, Lab Use Only.

Sodium danshensu (Sanshensu sodium, Salvianic acid A) is an orally active phenolic compound from Salvia miltiorrhiza within antioxidant, anti-inflammatory, and pro-angiogenesis effects, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway, reduces reactive oxygen species (ROS) production and upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway, also inhibits SARS-CoV-2 with EC50 of 0.97 uM, also directly inhibits calpain-2 (CAPN2).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Sodium danshensu (Sanshensu sodium, Salvianic acid A) is an orally active phenolic compound from Salvia miltiorrhiza within antioxidant, anti-inflammatory, and pro-angiogenesis effects, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway, reduces reactive oxygen species (ROS) production and upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway, also inhibits SARS-CoV-2 with EC50 of 0.97 uM, also directly inhibits calpain-2 (CAPN2).

Physicochemical Properties

M.Wt 220.16
Formula C9H9NaO5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

sodium (R)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoate

References

1. Zhang X, et al. Br J Pharmacol. 2026 Aug 19. doi: 10.1111/bph.70644.

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