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Chemical Structure : Solcitinib
CAS No.: 1206163-45-2
Catalog No.: PC-45072Not For Human Use, Lab Use Only.
Solcitinib (GSK2586184, GLPG0778) is a potent, selective and orally active JAK1 inhibitor with IC50 of 9.8 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg (Free Sample) | $28 | In stock | |
| 25 mg | $158 | In stock | |
| 50 mg | $238 | In stock | |
| 100 mg | $388 | In stock | |
| 250 mg | Get quote |
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Solcitinib (GSK2586184, GLPG0778) is a potent, selective and orally active JAK1 inhibitor with IC50 of 9.8 nM.
Solcitinib (GSK2586184, GLPG0778) displays 11-, 55- and 23-fold selectivity over JAK2, JAK3 and TYK2, respectively.
Solcitinib (GSK2586184, GLPG0778) shows potential for the treatment of psoriasis, lupus, and ulcerative colitis.
| M.Wt | 389.4503 | |
| Formula | C22H23N5O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: 20 mg/mL |
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| Chemical Name/SMILES |
Cyclopropanecarboxamide, N-[5-[4-[(3,3-dimethyl-1-azetidinyl)carbonyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]- |
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1. Ludbrook VJ, et al. Br J Dermatol. 2016 May;174(5):985-95.
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