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Sophoridine

Chemical Structure : Sophoridine

CAS No.: 6882-68-4

Sophoridine

Catalog No.: PC-27840Not For Human Use, Lab Use Only.

Sophoridine is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens with anticancer efficacy, inhibits HHV-6 replication, inhibits proliferation and migration by targeting PIM1 in breast cancer, inhibits the phosphorylation of ASK1 and activated JNK/p38 MAPK signaling pathway by downregulating PIM1 expression.

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100 mg $88 In stock
250 mg $128 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Sophoridine is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens with anticancer efficacy, inhibits HHV-6 replication, inhibits proliferation and migration by targeting PIM1 in breast cancer, inhibits the phosphorylation of ASK1 and activated JNK/p38 MAPK signaling pathway by downregulating PIM1 expression.

Physicochemical Properties

M.Wt 248.37
Formula C15H24N2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(41S,7aR,13aR,13bR)-Dodecahydro-1H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10(41H)-one

References

1. Qavi HB, et al. Phytother Res. 2002 Mar;16(2):154-6.

2. Dai L, et al. ChemMedChem. 2024 Jan 15;19(2):e202300467.

3. Chen L, et al. Pharm Biol. 2025 Dec;63(1):503-523.

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