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Sortin1

Chemical Structure : Sortin1

CAS No.: 503837-98-7

Sortin1 (Sortin-1)

Catalog No.: PC-43236Not For Human Use, Lab Use Only.

Sortin1 is a small molecule sorting inhibitor (Sortin) that induces reversible defects in vacuole biogenesis and root development in Arabidopsis seedlings at 100 mg/liter (227 uM).

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    Biological Activity

    Sortin1 is a small molecule sorting inhibitor (Sortin) that induces reversible defects in vacuole biogenesis and root development in Arabidopsis seedlings at 100 mg/liter (227 uM).
    Sortin1 induces secretion of the AtCPY (carboxypeptidase Y) precursor in Arabidopsis cell suspensions.
    Sortin1 is a powerful chemical to control the induced phenotype in a manner that would be difficult to achieve using conventional genetics.

    Physicochemical Properties

    M.Wt 441.4322
    Formula C26H19NO6
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1H-Indeno[1,2-b]pyridine-3-carboxylic acid, 4-[5-(4-carboxyphenyl)-2-furanyl]-4,5-dihydro-2-methyl-5-oxo-, 3-methyl ester

    References

    1. Zouhar J, et al. Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9497-501.

    2. Rosado A, et al. Chem Biol. 2011 Feb 25;18(2):187-97.

    3. Komatsu R, et al. Bioorg Med Chem Lett. 2018 Mar 23. pii: S0960-894X(18)30255-5.

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