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Chemical Structure : Sotorasib racemate
CAS No.: 2252403-56-6
Catalog No.: PC-73069Not For Human Use, Lab Use Only.
Sotorasib (AMG510) racemate is an orally active racemate of Sotorasib (AMG510), a potent, selective, covalent KRAS G12C inhibitor.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $228 | In stock | |
| 100 mg | $368 | In stock | |
| 250 mg | Get quote |
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Sotorasib (AMG510) racemate is an orally active racemate of Sotorasib (AMG510), a potent, selective, covalent KRAS G12C inhibitor.
| M.Wt | 560.61 | |
| Formula | C30H30F2N6O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-((S)-4-acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidin-2(1H)-one |
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1. Lanman BA, et al. J Med Chem. 2020 Jan 9;63(1):52-65.
2. Canon J, et al. Nature. 2019 Nov;575(7781):217-223.
3. Ryan MB, et al. Clin Cancer Res. 2020 Apr 1;26(7):1633-1643.
4. McCormick F. Cancer Cell. 2020 Jan 13;37(1):3-4.
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