Chemical Structure : Sotorasib racemate
CAS No.:
2252403-56-6
Sotorasib racemate
(AMG510 racemate)
Catalog No.: PC-73069Not For Human Use, Lab Use Only.
Sotorasib (AMG510) racemate is an orally active racemate of Sotorasib (AMG510), a potent, selective, covalent KRAS G12C inhibitor.
| Packing | Price | Stock | Quantity |
| 10 mg | $88 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $228 | In stock | |
| 100 mg | $368 | In stock | |
| 250 mg | | Get quote | |
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Purity & Documentation Purity:
>98% (HPLC)
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Biological Activity
Sotorasib (AMG510) racemate is an orally active racemate of Sotorasib (AMG510), a potent, selective, covalent KRAS G12C inhibitor.
Physicochemical Properties
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M.Wt
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560.61
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Formula
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C30H30F2N6O3
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Appearance
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Solid
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CAS No.
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Storage
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- Solide Powder
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-20°C 12 Months; 4°C 6 Months
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- In Solvent
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-80°C 6 Months; -20°C 6 Months
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Shipping
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Solubility
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10 mM in DMSO
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Chemical Name/SMILES
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4-((S)-4-acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidin-2(1H)-one
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References
1. Lanman BA, et al. J Med Chem. 2020 Jan 9;63(1):52-65.
2. Canon J, et al. Nature. 2019 Nov;575(7781):217-223.
3. Ryan MB, et al. Clin Cancer Res. 2020 Apr 1;26(7):1633-1643.
4. McCormick F. Cancer Cell. 2020 Jan 13;37(1):3-4.
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