StagX1

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Chemical Structure : StagX1

CAS No.: 868224-64-0

Catalog No.: PC-27933Not For Human Use, Lab Use Only.

StagX1 is a specific small molecule that inhibit the growth of Ewing sarcoma cells possessing mutant Stromal Antigen 2 (STAG2, SA2), selectively targets carboxylesterase 1 (CES1)-positive Ewing sarcoma cells.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

StagX1 is a specific small molecule that inhibit the growth of Ewing sarcoma cells possessing mutant Stromal Antigen 2 (STAG2, SA2), selectively targets carboxylesterase 1 (CES1)-positive Ewing sarcoma cells.

Physicochemical Properties

M.Wt	452.46
Formula	C24H24N2O7
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	ethyl 2-((2-(2-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)amino)-2-oxoethyl)-1-oxo-1,2-dihydroisoquinolin-5-yl)oxy)propanoate

References

1. Zhang N, et al. ChemMedChem. 2022 May 4;17(9):e202100653.

2. Zhang N, et al. Mol Ther Oncol. 2026 Aug 11;34(3):201321.

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StagX1

Biological Activity

Physicochemical Properties

References

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