Chemical Structure : Steroid sulfatase inhibitor DU-14
CAS No.: 186303-55-9
Catalog No.: PC-23217Not For Human Use, Lab Use Only.
Steroid sulfatase inhibitor DU-14 is a hihly potent steroid sulfatase inhibitor with IC50 of 55.8 nM, inhibits inhibits the MCF-7 cell proliferation with IC50 of 38.7 nM.
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Steroid sulfatase inhibitor DU-14 is a hihly potent steroid sulfatase inhibitor with IC50 of 55.8 nM, inhibits inhibits the MCF-7 cell proliferation with IC50 of 38.7 nM.
DU-14 shows neuroprotective effects against neurotoxic Aβ, alleviates Aβ-induced impairments in spatial memory and synaptic plasticity.
DU-14 can potentiate the blockade of the amnestic effects of scopolamine by exogenously administered DHEAS.
DU-14 enhanced the reversal of amnesia by DHEAS.
M.Wt | 426.62 | |
Formula | C22H38N2O4S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-[2-[4-[(Aminosulfonyl)oxy]phenyl]ethyl]tetradecanamide |
1. Li PK, et al. Life Sci. 1997;60(3):PL45-51.
2. Johnson DA, et al. Life Sci. 1997;61(24):PL 355-9.
3. Selcer KW, et al. Cancer Res. 1997 Feb 15;57(4):702-7.
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