Chemical Structure : Suvorexant
Catalog No.: PC-60062Not For Human Use, Lab Use Only.
Suvorexant (MK-4305, MK4305) is a potent, CNS penetrant, orally available, dual orexin receptor antagonist with Ki of 0.55 and 0.35 nM for OX1R and OX2R, respectively.
Bulk size, bulk discount!
Welcome credit card payment!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Suvorexant (MK-4305, MK4305) is a potent, CNS penetrant, orally available, dual orexin receptor antagonist with Ki of 0.55 and 0.35 nM for OX1R and OX2R, respectively.
Suvorexant significantly and dose-dependently reduces locomotor activity and promotes sleep in rats.
M.Wt | 450.92 | |
Formula | C23H23ClN6O2 | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
1. Cox CD, et al. J Med Chem. 2010 Jul 22;53(14):5320-32.
2. Winrow CJ, et al. J Neurogenet. 2011 Mar;25(1-2):52-61.
3. Sun H, et al. Sleep. 2013 Feb 1;36(2):259-67.
4. Hopkins CR. ACS Chem Neurosci. 2012 Sep 19;3(9):647-8.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright