Catalog No.: PC-61037Not For Human Use, Lab Use Only.
T-3364366 is a potent, selective and orally available inhibitor of delta-5 desaturase (D5D) with Ki of <2.7 nM and IC50 of 19 nM, with excellent selectivity over D6D and SCD.
T-3364366 is a potent, selective and orally available inhibitor of delta-5 desaturase (D5D) with Ki of <2.7 nM and IC50 of 19 nM, with excellent selectivity over D6D and SCD.
T-3364366 potently inhibits arachidonic acid (AA) production in liver cell lines derived from human (HepG2) and rat (RLN-10) with IC50 of 1.9 and 2.1 nM, respectively.
T-3364366 exhibits a reversible, slow-binding interaction to the desaturase domain of D5D.
