Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : T5342126 hydrochloride
Catalog No.: PC-63373Not For Human Use, Lab Use Only.
T5342126 hydrochloride is a potent, selective TLR4 inhibitor, inhibits LPS-induced NO production in RAW 264 macrophage cells with IC50 of 27.8 uM.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
T5342126 hydrochloride is a potent, selective TLR4 inhibitor, inhibits LPS-induced NO production in RAW 264 macrophage cells with IC50 of 27.8 uM.
T5342126 shows effectivity in reducing ethanol drinking and inhibiting the activation and proliferation of microglia in both ethanol-dependent and non-dependent mice.
| M.Wt | 494.457 | |
| Formula | C25H33Cl2N3O3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Bajo M, et al. Alcohol. 2016 Sep;51(5):541-8.
2. Chavez SA, et al. J Med Chem. 2011 Jul 14;54(13):4659-69.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
