T6I-29-1A | SERM | Probechem Biochemicals

Chemical Structure : T6I-29-1A

T6I-29-1A (Selective estrogen receptor modulator)

Catalog No.: PC-22504Not For Human Use, Lab Use Only.

T6I-29-1A is the active enantiomer of T6I-29, which is a novel isoquinoline-based selective estrogen receptor modulator (SERM), interacts with Y537S ERα ligand binding domain (LBD), exhibits anti-proliferative activities.

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Biological Activity

Physicochemical Properties

M.Wt	514.64
Formula	C32H35FN2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(1'-(4-((1-(3-fluoropropyl)pyrrolidin-3-yl)methoxy)phenyl)-6'-hydroxy-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-isoquinolin]-2'-yl)(phenyl)methanone

References

1. Young KS, et al. bioRxiv [Preprint]. 2024 Jun 2:2024.05.28.596307.

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T6I-29-1A (Selective estrogen receptor modulator)

Biological Activity

Physicochemical Properties

References

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