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TAK-448

Chemical Structure : TAK-448

CAS No.: 1234319-68-6

TAK-448 (MVT-60, TAK448)

Catalog No.: PC-22641Not For Human Use, Lab Use Only.

TAK-448 (MVT-602) is a potent and full KISS1R (metastin receptor) agonist and kisspeptin analogue with IC50 of 3 pM in radioimmunoassay.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

TAK-448 (MVT-60, TAK448) is a potent and full KISS1R (metastin receptor) agonist and kisspeptin analogue with IC50 of 3 pM in radioimmunoassay.

Physicochemical Properties

M.Wt 1225.38
Formula C58H80N16O14
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

L-Tryptophanamide, N-acetyl-D-tyrosyl-(4R)-4-hydroxy-L-prolyl-L-asparaginyl-L-threonyl-L-phenylalanyl-2-azaglycyl-L-leucyl-N5-[imino(methylamino)methyl]-L-ornithyl-

References

1. Yoshida N, et al. J Pharm Biomed Anal. 2012 Nov;70:369-77.

2. Matsui H, et al. Endocrinology. 2012 Nov;153(11):5297-308.

3. Matsui H, et al. Eur J Pharmacol. 2014 Jul 15;735:77-85.

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