Catalog No.: PC-72749Not For Human Use, Lab Use Only.
Danavorexton (TAK-925) is a potent, selective, and brain-penetrant Orexin 2 receptor (OX2R) agonist with EC50 of 5.5 nM, no significant inhibition on OX1R (IC50>100 uM).
Danavorexton (TAK-925) is a potent, selective, and brain-penetrant Orexin 2 receptor (OX2R) agonist with EC50 of 5.5 nM, no significant inhibition on OX1R (IC50>100 uM).
TAK-925 also showed good selectivity against 106 off-target enzymes and receptors.
TAK-925 produced wake-promoting effects in mice during the sleep phase, being developed for the treatment of narcolepsy and other related disorders.
