Chemical Structure : TAPI-0
CAS No.: 163958-73-4
Catalog No.: PC-21091Not For Human Use, Lab Use Only.
TAPI-0 is a potent, selective inhibitor of TNFalpha converting enzyme (TACE, ADAM7) with IC50 of 100 nM.
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TAPI-0 is a potent, selective inhibitor of TNFalpha converting enzyme (TACE, ADAM7) with IC50 of 100 nM.
M.Wt | 456.54 | |
Formula | C24H32N4O5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-L-alaninamide |
1. Kagawa K, et al. PLoS One. 2012;7(2):e31594.
2. Kruse MN, et al. Biochem J. 2004 Mar 1;378(Pt 2):383-9.
3. Shiori Haga, et al. Antiviral Res. 2010 Mar;85(3):551-5.
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