TAPI-0

Chemical Structure : TAPI-0

CAS No.: 163958-73-4

Catalog No.: PC-21091Not For Human Use, Lab Use Only.

TAPI-0 is a potent, selective inhibitor of TNFalpha converting enzyme (TACE, ADAM7) with IC50 of 100 nM.

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Biological Activity

TAPI-0 is a potent, selective inhibitor of TNFalpha converting enzyme (TACE, ADAM7) with IC50 of 100 nM.

M.Wt	456.54
Formula	C24H32N4O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-L-alaninamide

1. Kagawa K, et al. PLoS One. 2012;7(2):e31594.

2. Kruse MN, et al. Biochem J. 2004 Mar 1;378(Pt 2):383-9.

3. Shiori Haga, et al. Antiviral Res. 2010 Mar;85(3):551-5.