TAPI-1

Chemical Structure : TAPI-1

CAS No.: 163847-77-6

Catalog No.: PC-21092Not For Human Use, Lab Use Only.

TAPI-1 is a small molecule inhibitor of TNFalpha converting enzyme (TACE, ADAM7), blocks the shedding of several cell surface proteins.

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Biological Activity

TAPI-1 is a small molecule inhibitor of TNFalpha converting enzyme (TACE, ADAM7), blocks the shedding of several cell surface proteins.

M.Wt	499.61
Formula	C26H37N5O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N1-((S)-1-(((S)-1-((2-Aminoethyl)amino)-1-oxopropan-2-yl)amino)-3-(naphthalen-2-yl)-1-oxopropan-2-yl)-N4-hydroxy-2-isobutylsuccinamide

1. Bae EH, et al. Korean J Physiol Pharmacol. 2018 Mar;22(2):135-143.

2. Jolly-Tornetta C, et al. Biochemistry. 2000 Dec 12;39(49):15282-90.