TC-5115 | MLL1 SET domain | Probechem Biochemicals

Chemical Structure : TC-5115

TC-5115 (TC5115)

Catalog No.: PC-72008Not For Human Use, Lab Use Only.

TC-5115 (TC5115 ) is a potent, selective inhibitor of MLL1 SET domain with IC50 of 15 nM, 48 times more potent than the pan-methyltransferase inhibitor SAH.

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Biological Activity

TC-5115 (TC5115 ) is a potent, selective inhibitor of MLL1 SET domain with IC50 of 15 nM, 48 times more potent than the pan-methyltransferase inhibitor SAH.

Physicochemical Properties

M.Wt	532.62
Formula	C23H32N8O5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-amino-4-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)((1-(thiophen-2-ylmethyl)azetidin-3-yl)methyl)amino)butanoic acid

References

1. Chern TR, et al. ACS Med Chem Lett. 2020 May 14;11(6):1348-1352.

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TC-5115 (TC5115)

Biological Activity

Physicochemical Properties

References

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