TC-S7009 | HIF2α inhibitor | Probechem Biochemicals

Chemical Structure : TC-S7009

CAS No.: 1422955-31-4

TC-S7009 (TC-S 7009 )

Catalog No.: PC-22317Not For Human Use, Lab Use Only.

TC-S7009 is a specific inhibitor of HIF-2α with Kd of 81 nM, disrupts HIF-2α′s heterodimerization and DNA-binding activity, reducing the expression of HIF-2α-dependent genes.

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25 mg	$218	In stock
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Biological Activity

TC-S7009 is a specific inhibitor of HIF-2α with Kd of 81 nM, disrupts HIF-2α′s heterodimerization and DNA-binding activity, reducing the expression of HIF-2α-dependent genes.

Physicochemical Properties

M.Wt	308.65
Formula	C12H6ClFN4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-chloro-5-fluorophenyl)-4-nitrobenzo[c][1,2,5]oxadiazol-5-amine

References

1. Scheuermann TH, et al. Nat Chem Biol. 2013 Apr;9(4):271-6.

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TC-S7009 (TC-S 7009 )

Biological Activity

Physicochemical Properties

References

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