TCDMC-143160 | TcTDH inhibitor | Probechem Biochemicals

Chemical Structure : TCDMC-143160

TCDMC-143160 (TCDMC143160)

Catalog No.: PC-23626Not For Human Use, Lab Use Only.

TCDMC-143160 is a specific inhibitor of T. cruzi L-threonine dehydrogrenase (TcTDH) with IC50 of 3.5 uM, inhibits the threonine degradation pathway and interferes with parasite growth and viability.

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Biological Activity

TCDMC-143160 is a specific inhibitor of T. cruzi L-threonine dehydrogrenase (TcTDH) with IC50 of 3.5 uM, inhibits the threonine degradation pathway and interferes with parasite growth and viability.

Physicochemical Properties

M.Wt	271.32
Formula	C16H17NO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-N-(4-ethoxyphenyl)-3-(5-methylfuran-2-yl)acrylamide

References

1. Faria JDN, et al. J Biol Chem. 2024 Dec 13:108080.

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TCDMC-143160 (TCDMC143160)

Biological Activity

Physicochemical Properties

References

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