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TCID

Chemical Structure : TCID

CAS No.: 30675-13-9

TCID (UCHL3 inhibitor TCID)

Catalog No.: PC-61702Not For Human Use, Lab Use Only.

TCID is a selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor with IC50 of 0.6 uM, displays >100-fold selectivity over UCH-L1.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

TCID is a selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor with IC50 of 0.6 uM, displays >100-fold selectivity over UCH-L1.
TCID diminishes glycine transporter GlyT2 ubiquitination in brain stem and spinal cord primary neurons.

Physicochemical Properties

M.Wt 283.9
Formula C9H2Cl4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4,5,6,7-Tetrachloro-1H-Indene-1,3(2H)-dione

References

1. Liu Y, et al. Chem Biol. 2003 Sep;10(9):837-46.

2. de Juan-Sanz J, et al. PLoS One. 2013;8(3):e58863.

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